Prognostic value of the immune microenvironment in lung adenocarcinoma

نویسندگان

  • Kyuichi Kadota
  • Jun-ichi Nitadori
  • Prasad S. Adusumilli
چکیده

We analyzed the immune microenvironment in the neoplastic and stromal components of Stage I lung adenocarcinoma lesions, finding that a high ratio of tumor-infiltrating FOXP3+ regulatory T cells to CD3+ lymphocytes, an elevated expression of the interleukin-7 receptor, as well as a reduced expression of the interleukin-12 receptor β2 all constitute independent factors of poor prognosis.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2013